Lasix chemical name

The chemical name for Lasix is furosemide.

Furosemide Properties

Furosemide is a potent loop diuretic. It works by inhibiting the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle in the kidneys. This mechanism prevents reabsorption of sodium, chloride, and water, leading to increased urine production.

Lasix and its Chemical Structure

Understanding the chemical structure aids in comprehension of its pharmacodynamic properties. The molecule contains a sulfonamide group, a crucial component for its diuretic activity.

Property	Value
Chemical Formula	C₁₂H₁₁ClN₂O₅S
Molecular Weight	330.73 g/mol
CAS Registry Number	54-31-9

Further Information

Consult a healthcare professional or refer to a pharmaceutical reference for detailed information regarding Lasix, including dosage, side effects and interactions.

Chemical Name and IUPAC Nomenclature

Lasix’s chemical name is furosemide. The IUPAC nomenclature, providing a systematic and unambiguous name, is 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid.

This name precisely describes the molecule’s structure, allowing chemists worldwide to easily identify and synthesize it. Note the components explicitly defining the molecule: “4-chloro” indicates a chlorine atom at the fourth position; “N-furfuryl” specifies a furfuryl group attached to a nitrogen atom; “5-sulfamoylanthranilic acid” denotes a sulfamoyl group at the fifth position and the anthranilic acid core structure.

Understanding this nomenclature is critical for accurately communicating the drug’s identity in research, manufacturing, and regulatory settings. Accurate chemical naming prevents confusion and ensures the correct drug is handled.

Remember: Using the IUPAC name avoids ambiguity and is preferred in scientific publications and formal documentation related to furosemide.

Molecular Formula and Structure

Lasix, also known as furosemide, possesses the molecular formula C₁₂H₁₁ClN₂O₅S. This formula precisely indicates the number and type of atoms constituting a single furosemide molecule.

Visual Representation

Understanding the arrangement of these atoms is crucial. The following points highlight key structural features:

A benzene ring forms the core of the structure.
A sulfamoyl group (-SO₂NH₂) is attached to the benzene ring.
A chlorine atom is substituted on the benzene ring.
A carboxyl group (-COOH) contributes to the molecule’s acidity.
A carbonyl group (-C=O) and an ethyl group (-CH₂CH₃) are additional key features.

These components interact to create a unique three-dimensional structure with specific properties influencing its pharmacological activity.

Structural Isomers

It’s important to note that subtle changes in the arrangement of atoms can significantly alter the drug’s properties. The precise arrangement detailed above distinguishes furosemide from its potential structural isomers. Variations in substitution patterns on the benzene ring or alterations in the side chains could result in dramatically different biological effects.

Simplified Diagram

While a complete 3D model is ideal, a simplified 2D representation can also be helpful to visualize the fundamental structure. (Note: A visual diagram would be included here in a complete article, but is omitted due to the limitations of this text-based format.)

The image would clearly show the benzene ring.
The positions of the chlorine, sulfamoyl, and carboxyl groups would be clearly identified.
The ethyl and carbonyl groups would be readily apparent.

Reference to scientific databases and chemical structure drawing software will provide a more detailed and accurate representation.

Synonyms and Trade Names

The chemical name for Lasix is furosemide. This is the official name used in scientific literature and regulatory documents.

However, you’ll find Lasix sold under many different brand names globally. Some examples include Furosemide (generic), Lasix (the most common brand name), and Urex.

Remember that the specific brand names available vary significantly depending on your location and the pharmaceutical company distributing the drug. Always check the label for the active ingredient, furosemide, to ensure you’re receiving the correct medication.

Consult a pharmacist or physician for further clarification on specific brand names available in your region.

Chemical Properties and Stability

Lasix, or furosemide, presents as a white to slightly yellowish crystalline powder. It’s practically insoluble in water, but readily dissolves in dilute solutions of alkali hydroxides. This solubility characteristic is crucial for formulation development.

Solubility and pKa

The pKa of furosemide is approximately 3.9. This means it exhibits significant ionization at physiological pH (around 7.4), influencing its absorption and distribution in the body. Its low water solubility necessitates careful consideration during formulation, often requiring the use of solubilizing agents.

Stability Considerations

Furosemide is relatively stable under typical storage conditions (room temperature, protected from light and moisture). However, solutions can degrade over time, particularly in the presence of high temperatures or extreme pH values. Hydrolysis is a possible degradation pathway. Manufacturers recommend specific storage conditions to ensure drug potency. Degradation products should be monitored during stability testing. Observe expiration dates for optimal efficacy.

Light Sensitivity

Exposure to light can accelerate degradation. Therefore, protective packaging minimizes this risk and ensures product stability.

Relevance of Chemical Information for Healthcare Professionals

Knowing the chemical name of Lasix (furosemide) allows for precise medication identification, avoiding potential confusion with similar-sounding drugs. This precision is critical for accurate prescribing and patient safety.

Understanding Drug Interactions

Furosemide’s chemical structure informs understanding of its interactions with other medications. This knowledge helps predict and manage potential adverse effects. For example, concurrent use with certain antibiotics may necessitate dosage adjustments.

Consult drug interaction databases regularly to stay updated.
Monitor patients closely for any unexpected reactions.

Pharmacokinetics & Pharmacodynamics

The chemical structure provides clues to how furosemide is absorbed, distributed, metabolized, and excreted. This knowledge, combined with patient-specific factors (age, renal function, etc.), informs appropriate dosing strategies and monitoring plans.

Consider renal function before prescribing.
Adjust dosages based on patient’s response and lab results.
Be aware of potential for drug accumulation in renal impairment.

Patient Education & Counseling

While you don’t need to disclose the entire chemical structure to a patient, understanding furosemide’s chemical properties helps you explain its mechanism of action more accurately. This facilitates more effective patient education and medication adherence.

Clearly explain the drug’s function and potential side effects.
Address patient concerns about medication safety.

Adverse Event Reporting & Research

Precise chemical information is crucial for reporting adverse drug events and participating in pharmacovigilance activities. Accurate data improves drug safety monitoring and contributes to future research on furosemide and related diuretics.

Report any unusual or unexpected reactions promptly.
Stay current with research findings on furosemide’s effects.

Chemical Purity & Quality Control

Understanding the chemical composition is vital for ensuring the purity and quality of furosemide preparations. This impacts therapeutic efficacy and reduces the risk of adverse effects from impurities.

Source medications from reputable suppliers.
Review quality control data where available.

Lasix chemical name